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99% Purity Antidote Raw White Powder Flumazenil For Nootropic Supplement

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99% Purity Antidote Raw White Powder Flumazenil For Nootropic Supplement

China 99% Purity Antidote Raw  White Powder Flumazenil For Nootropic Supplement supplier
99% Purity Antidote Raw  White Powder Flumazenil For Nootropic Supplement supplier 99% Purity Antidote Raw  White Powder Flumazenil For Nootropic Supplement supplier 99% Purity Antidote Raw  White Powder Flumazenil For Nootropic Supplement supplier

Large Image :  99% Purity Antidote Raw White Powder Flumazenil For Nootropic Supplement

Product Details:

Place of Origin: HUBEI,CHINA
Brand Name: HKYC
Certification: ISO 9000, SGS
Model Number: Nootropics

Payment & Shipping Terms:

Minimum Order Quantity: 10grams
Price: negotiable(best offer will be provided)
Packaging Details: designed disguised packing ways, 100% pass custom guarantee)
Delivery Time: within 24hours after payment confirm
Payment Terms: MoneyGram, Western Union, T/T, Bitcoin
Supply Ability: 1000Kg per Month
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Detailed Product Description
Name: Flumazenil Purity: 99.5%
Ailas: Romazicon Appearence: White Powder
Export Market: Global Packing Methods: Designed Disguised Packing Ways, 100% Pass Custom Guarantee
Delivery Time: 3-7 Working Days Delivery Method: Ship By Express, Like EMS,DHL, Fedex, TNT, UPS, Aramex Etc
Shelf Life: 2years Payment Methods: T/T, Western Union, MoneyGram, Bitcoin

99% Purity Antidote Raw  White Powder Romazicon Flumazenil For Nootropic Supplement

 

 

1. Flumazenil Quick detail

 

 

Product Name Flumazenil
Alias Romazicon
CAS 78755-81-4
MF C15H14FN3O3
MW 303.29
Purity 99.50%
Grade Pharmaceutical Grade
Appearance clorless liquild
Brand Nmae HKYC
Standard USP
Stock Mass Stock
Shelf Life 2years
Packing Methods foil bag or as your mind
Delivery time within 18 hours after payment confirmed
Payment T/T, Western Union,Money Gram , Bitcoin
Usage Fumazenil is an imidazobenzodiazepine derivative.
Fumazenil a potent benzodiazepine receptor antagonist.

 


2. Fumazenil Description

Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.

3. Flumazenil Half life

Initial distribution half-life is 4 to 11 minutes and the terminal half-life is 40 to 80 minutes. Prolongation of the half-life to 1.3 hours in patients with moderate hepatic impairment and 2.4 hours in severely impaired patients. Compared to adults, the elimination half-life in pediatric patients was more variable, averaging 40 minutes (range: 20 to 75 minutes).

4.Flumazenil Applications


Flumazenil is of benefit in patients who become excessively drowsy after benzodiazepines are used for either diagnostic or therapeutic procedures.

It has been used as an antidote in the treatment of benzodiazepine overdoses.It reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine binding site on the GABAA receptor. There are many complications that must be taken into consideration when used in the acute care setting.These include lowered seizure threshold, agitation, and anxiousness. Flumazenil's short half-life requires multiple doses and careful patient monitoring to prevent recurrence of overdose symptoms.

It is also sometimes used to reverse the effects of benzodiazepines after surgery in a manner similar to naloxone's application to reverse the effect of opiates and opioid following surgery. This requires careful monitoring by an anesthesiologist due to potential side effects and serious risks associated with both over-administering flumazenil and the removal of patient life-support and monitoring equipment before the benzodiazepines have worn off (due to flumazenil masking their continued effect).

Flumazenil has been effectively used to treat overdoses of non-benzodiazepine hypnotics, such as zol-pidem,.

It may also be effective in reducing excessive daytime sleepiness while improving vigilance in primary hypersomnias, such as idiopathic hypersomnia.

It has also been used in hepatic encephalopathy, though results have been mixed.

The onset of action is rapid and usually effects are seen within one to two minutes. The peak effect is seen at six to ten minutes. The recommended dose for adults is 200 μg every 1-2 minutes until the effect is seen, to a maximum of 3 mg per hour. It is available as a clear, colourless solution for intravenous injection, containing 500 μg in 5 mL.

 

5. Flumazenil Specification

 

Items of analysis Specification Results
Appearance White crystalline powder White Crystalline Powder
Identification The sample'S IR spectrum is according with spectrum of Flumazenil,The retention time of the major peak Flumazenil in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation Conforms
Melting point 198ºC to 202ºC 200.6ºC to 200.9ºC
Appearance of solution The solution is clear and is not Intenser than reference solution BY7 Conforms
Impurity C NMT 0.2% 0.02%
Impurity A NMT 0.10% Not detected
Impurity B NMT 0.2% 0.03%
Impurity D NMT 0.10% 0.03%
Impurity E NMT 0.10% Not detected
Impurity F NMT 0.10% Not detected
Individual unknown impurituy NMT 0.10% 0.02%
Total impurities NMT 0.5% 0.1%
Loss on drying NMT 0.5% 0.2%
Sulphated ash NMT 0.1% 0.05%
Heavy metals ≤0.5 ppm 5ppm
Microbial limits( for Injection) Bacteria not more than 50CFU/g <10 CFU/g
Microbial limits Mildew and microzyme not more than 50CFU/g <10 CFU/g
Microbial limits Escherichia coli absence Absence
Ethanol NMT2000ppm Not detected
Chloroform NMT30ppm Not detected
Acetic acid NMT4000ppm Not detected
Dichloromethane NMT600ppm <0.002%
Ethyl ethanoate NMT5000ppm <0.003%
DMF NMT750ppm Not detected
Assay (On dried substance) 98.0-102.0% 99.80%
Bacterial endotoxins not more than 25.0 USP Endotoxin Units per mg of flumazenil. not more than 8.0 USP Endotoxin Units per mg of flumazenil.
Guarantees the nature time 36 months 36 months

 

 

99% Purity Antidote Raw  White Powder Flumazenil For Nootropic Supplement

 

You may want to know First :

 

1. Available: steroid powder, semi-finished oil, sarms, peptides pain killers etc. And all kinds of machines for  steroids processing.

 

2. Parcel : Designed Discreet packing according to different countries and quantity.

 

3. Pass Custom Rate: more than 99%.

 

4. Reship Policy: we do reship once free (no country limitation) if the parcel be seized. Pls contatc whatsapp +8618872220826.


5. Delivery Methods: EMS, DHL, FedEx, UPS, TNT, Aramex, China/Hongkong/ Singapore/Sweden/Holland Post Mail. All with tracking code. Usual delivery time is 4-7 workdays.

6.Delivery Time: US :3-5 days, UK: 4-7 days, Canada: 3-7 days, Europe: 6-10 days

 

Packaging & Service:


1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 25 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking code are provided within 24 hours as soon as receiving the payment. Updated tracking code will be provided every other day just for you can hold a palm of your package.
5. Perfect after-sale service: Any questions or problems happened after receiving the product.

 

 

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Contact Details
Hongkong YuanCheng GongChuang Technology Co.,Ltd

Contact Person: Athena

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