Fitness Nutrition SARMs Steroid Raw Powder SR9011 for Fat Burner

Fitness Nutrition SARMs Steroid Raw Powder SR9011 for Fat Burner 

SR9011 Basic Info

SR9011 Descprtion:

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.

A new compound called SR9011 increases metabolism, fat burning, and muscle growth in the lab.
Scientists at The Scripps Research Institute (TSRI) have successfully tested a drug, called SR9011,
in mice that kickstarts metabolism and results in increased muscle development.
Essentially, it's an exercise regime in a pill.

SR9011 Application

SR9011 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed [in]
animals [that] are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify
its metabolism.

Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that a small, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance
SR9011 increases metabolism, fat burning, and muscle growth in the lab.

Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic.

How to Use SR9011

In vitro: SR9011 was used at 5-10 μM concentration in vitro and in cellular assays.
In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.

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