Prohormone Estrogen Steroids Powder Estradiol For Female Sexual Development

Prohormone Estrogen Steroids Powder Estradiol For Female Sexual Development

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Estradiol Quick Details

Estradiol Description 

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues. but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well.

Estradiol Applications:

1. Sexual development

The development of secondary sex characteristics in women is driven by estrogens, to be specific, estradiol. These changes are initiated at the time of puberty, most are enhanced during the reproductive years, and become less pronounced with declining estradiol support after the menopause. Thus, estradiol produces breast development, and is responsible for changes in the body shape, affecting bones, joints, and fat deposition. Fat structure and skin composition are modified by estradiol.

2. Female reproduction

In the female, estradiol acts as a growth hormone for tissue of the reproductive organs, supporting the lining of the vagina, the cervical glands, the endometrium, and the lining of the fallopian tubes. Estradiol enhances growth of the myometrium. Estradiol appears necessary to maintain oocytes in the ovary.

During the menstrual cycle, estradiol produced by the growing follicle triggers, via a positive feedback system, the hypothalamic-pituitary events that lead to the luteinizing hormone surge, inducing ovulation. In the luteal phase, estradiol, in conjunction with progesterone, prepares the endometrium for implantation.

3. Male reproduction

The effect of estradiol (and estrogens in general) upon male reproduction is complex. Estradiol is produced by action of aromatase mainly in the Leydig cells of the mammalian testis, but also by some germ cells and the Sertoli cells of immature mammals.

Estradiol functions (in vitro) to prevent apoptosis of male sperm cells. While some studies in the early 1990s claimed a connection between globally declining sperm counts and estrogen exposure in the environment, later studies found no such connection, nor evidence of a general decline in sperm counts. Suppression of estradiol production in a subpopulation of subfertile men may improve the semen analysis.

Males with certain sex chromosome genetic conditions, such as Klinefelter's syndrome, will have a higher level of estradiol.

4. Bone

Estradiol has a profound effect on bone. Individuals without it (or other estrogens) will become tall and eunuchoid, as epiphyseal closure is delayed or may not take place. Bone structure is affected also, resulting in early osteopenia and osteoporosis.

Also, women past menopause experience an accelerated loss of bone mass due to a relative estrogen deficiency.

5. Brain

Estrogens can be produced in the brain from steroid precursors. As antioxidants, they have been found to have neuroprotective function.

The positive and negative feedback loops of the menstrual cycle involve ovarian estradiol as the link to the hypothalamic-pituitary system to regulate gonadotropins.

6. Gynecological cancers

Estradiol has been tied to the development and progression of cancers such as breast cancer, ovarian cancer and endometrial cancer.

Estradiol has complex effects on the liver. In high amounts, it can lead to cholestasis. Estradiol affects the production of multiple proteins, including lipoproteins, binding proteins, and proteins responsible for blood clotting.

Estrogen affects certain blood vessels. Improvement in arterial blood flow has been demonstrated in coronary arteries.

Several benign gynecologic conditions are dependent on estrogen, such as endometriosis, leiomyomata uteri, and uterine bleeding.

Estradiol Specification

Related Estrogen Steroid Powder

Estradiol benzoate CAS No.50-50-0
Estradiol CAS No.50-28-2
Estrone CAS No.53-16-7
Estradiol Enanthate CAS No.4956-37-0
Estradiol Cypionate CAS No.313-06-4
Diethylstilbestrol CAS NO.56-53-1,6898-97-1
Nilestriol CAS No.39791-20-3
T-ibolone(Livial;Liviella) CAS No.5630-53-5
Estradiol Valerate CAS No.979-32-8

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1. Available: steroid powder, semi-finished oil, sarms, peptides pain killers etc. And all kinds of machines for steroids processing.

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5. Delivery Methods: EMS, DHL, FedEx, UPS, TNT, Aramex, China/Hongkong/ Singapore/Sweden/Holland Post Mail. All with tracking code. Usual delivery time is 4-7 workdays.

6.Delivery Time: US :3-5 days, UK: 4-7 days, Canada: 3-7 days, Europe: 6-10 days

Packaging & Service:

1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 25 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
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