2mg/Vial Oxytocin Peptides Oxytocin Acetate CAS50-56-6 For Hasten Parturition

Oxytocin Acetate

Alias:Atonin,Endopituirina,Orasthin,Oxytocinum,Partocon,Pitocin,Piton,Pitupartin,Utedrin,Uteracon
Cas: 50-56-6
EINECS : 200-048-4
Molecular Formula: C43H66N12O12S2
Molecular Weight: 1007.19
Purity (HPLC): 98.0%min.
Appearance: White powder
Single Impurity (HPLC): 1.0%max
Storage: Closed, below 2 ~ 8ºC preservation

Usage : For induction of labor, postpartum oxytocin, and abortion due to uterine atony or retraction caused by the bad uterus bleeding; understand the placental function reserve (oxytocin challenge test); nasal drops can promote milk ejection.



Introduction

Oxytocin is a mammalian hormone that acts primarily as a neuromodulator in the brain. Oxytocin is best known for its roles in sexual reproduction, in particular during and after childbirth. It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, and after stimulation of the nipples, facilitating breastfeeding. The word oxytocin was derived from the Greek word", meaning quick birth. The oxytocin peptide is synthesized as an inactive precursor protein from the OXT gene.

Oxytocin is a peptide of nine amino acids (a nonapeptide). Its systematic name is cysteine-tyrosine-isoleucine-glutamine-asparagine-cysteine-proline-leucine-glycine-amine (cys, tyr, ile,gln,asn,cys, pro, leu, gly - NH2, or CYIQNCPLG-NH2). The cysteine residues form a disulfide bond. Oxytocin has a molecular mass of 1007 daltons. One international unit (IU) of oxytocin is the equivalent of about 2 micrograms of pure peptide. The trust-inducing property of oxytocin might help those who suffer from social anxieties and mood disorders, but with the potential for abuse with confidence tricks and military applications.

Application

Injected oxytocin analogues are used for labor induction and to support labor in case of difficult parturition. It has largely replaced ergometrine as the principal agent to increase uterine tone in acute postpartum hemorrhage. Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release. The tocolyticagent atosiban (Tractocile) acts as an antagonist of oxytocin receptors; this drug is registered in many countries to suppress premature labor between 24 and 33 weeks of gestation. It has fewer side effects than drugs previously used for this purpose (ritodrine, salbutamol, and terbutaline).

Usage And Dosage

Odinopoeia or oxytocin intravenous drip, once the 2.5 - 5 units, with Sodium Chloride Injection diluted to each 1ml contains 0.01 units. Intravenous drip of the beginning of every minute of not more than 0.001 to 0.002 units, each 15 - 30 minutes increased 0.001 to 0.002 units, to achieve the contractions and normal childbirth is similar, the fastest per minute of not more than 0.02 units, usually 0.002 to 0.005 units per minute.

Control postpartum hemorrhage per minute intravenous drip of 0.02 - 0.04 units, expulsion of the placenta after intramuscular injection of 5 to 10 units.
Lactogenic just before a 2 - 3 minutes, with nasal drops a 3 drop, drop into one side or both sides of the nostril.

Preparation and specification : oxytocin injection (1) 0.5ml:2.5 units (2) 1ml:5 (3) 1ml units 10 units;

Oxytocin nasal drops 1ml:40 units. The induction of labor or prenatal uterine atony: in 2.5-5 units in 500ml 5% glucose for intravenous drip slowly (10-30 drops / minute), maximum time 20 units. (2). Prevention of postpartum hemorrhage: intramuscular injection of 5-10 on each unit, or 5% glucose solution for intravenous drip.

The main contraindication, heart disease, a caesarean history and more than three fetal maternal disable.

What is oxytocin, what is it doing?

Oxytocin is a hormone made in the brain and hypothalamus. It is transported to the pituitary gland secretion at the base of the brain.Oxytocin is a powerful hormone that acts as a neurotransmitter in the brain. It regulates social interaction and sexual reproduction, playing a role in the act of combining mother-to-child and milk release into compassion, generosity and orgasm. When we hug or kiss a loved one, oxytocin levels increase; therefore, oxytocin is often referred to as "estrogen". In fact, hormones play a huge role in all matching. Hormones are greatly stimulated during sex, birth and breastfeeding. Oxytocin is the foundation of the hormone. It is also an antidote to depression.

However, for all positive, oxytocin has a dark side. Or, more precisely, it plays a more complex role than human beings in human behavior. As a facilitator of the association between people with similar characteristics, hormones can promote differences between members of the group and outside the group and favor the members of the group favoring the group members. Sustained research on hormones strongly suggests the complexity of biological and psychological systems.

In chemistry, oxytocin is classified as a nonpeptide (a peptide containing nine amino acids), and its biological classifications are neuropeptides. It acts both as a hormone and as a neurotransmitter.

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