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Anti Estrogen Toremifene Citrate / Fareston Powder CAS 89778-27-8
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Toremifene citrate is an oral selective estrogen receptor modulator which helps oppose the actions of estrogen in the body. Toremifene citrate is FDA-approved for use in advanced (metastatic)breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.
Antiestrogen Steroid Hormones Toremifene Citrate CAS: 89778-27-8
Tamoxifen Citrate Usage
In terms of dosing, sixty milligrams of toremifene citrate has been shown to be similar in effect to that of approximately twenty milligrams of tamoxifen citrate in terms of estrogen receptor binding ability.
In terms of dosing frequency, the drug has a fairly long active life therefore one could administer the compound once every few days. However to maintain fairly stable levels of the drug circulating in their system most users would be best served to administer the drug at least every other day or ideally every day. This ensures that there are no extreme spikes in the level of the drug and no severe tapering off
Fareston - Toremifene Citrate
Fareston (toremifene citrate) is a Selective Estrogen Receptor Modulator (SERM) derived from triphenylethelyne. It is Licensed in the United States under the brand name “Fareston” and currently FDA approved for use in advanced (metastatic) breast cancer. It is currently being studies for use in prostate cancer as well.
Toremifene Citrate exerts its effects by antagonizing the estrogen receptor in some tissues, and agonizing it in others. In this way, certain estrogenic pathways are activated and others are blockaded. It seems to exert estrogenic effects on blood lipids, reducing LDL and total cholesterol, as well as estrogenic effects on bone, improving density. It would also appear to exert anti-estrogenic effects in breast tissue, displacing the traditional effects of estrogen, effectively helping prevent breast cancer in postmenopausal women.
Fareston is a Selective Estrogen Receptor Modulator. Other drugs in this class are Clomid and Nolvadex. SERMs act by being an estrogen agonist in certain tissues and an estrogen antagonist in others.
In men, at the hypothalamus and pituitary, estrogen acts in cooperation with the body’s negative feedback loop to send a signal to decrease the secretion of LH. When LH secretion is lowered, so are natural testosterone levels. SERMs, like Fareston, possibly act as an estrogen antagonist in the hypothalamus and pituitary, in order to increase testosterone production. Thus, although it hasn’t been studied to any great degree, it’s highly likely that Fareston is capable (or better) of increasing testosterone in the same way that Nolvadex it, as it’s androgenicity:estrogenicity ratio is 5x that of Nolvadex (1). However, in terms of improving bone mineral density, Fareston is roughly equal to Nolvadex. (2) Fareston, like other SERMS, would appear to have very beneficial effects on blood lipid levels and other health markers.
Although some of the research looks promising, and it may be the case that Fareston can have potential to elevate testosterone levels higher than other SERMs being currently used by bodybuilders and athletes, the jury is still out on that.
There simply have not been enough people using Fareston for long enough to know where its place in the steroid using milieu will eventually be. For now, it can be considered to have potential, but nothing more. I have high hopes for this drug to live up to it’s potential, but only time will tell.
If you’re considering adding it into a cycle, just be sure to keep other ancillaries on hand, just in case.
Toremifene Citrate is the chemical name of active ingredient in Fareston. Fareston is a registered trademark of U.S. of GTx, Inc. in the United States and/or other countries.
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|Anti-Estrogens / PCT powders|
|Nolvadex (Tamoxifen Citrate)|
|Clomid (Clomiphene Citrate)|
|Fareston (Toremifene Citrate)|
|Evista (Raloxifene Hydrochloride)|