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Pharmaceutical Raw Materials Anticancer Drug Raw Ceritinib LDK378 For Cancer

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Pharmaceutical Raw Materials Anticancer Drug Raw Ceritinib LDK378 For Cancer

China Pharmaceutical Raw Materials Anticancer Drug Raw Ceritinib LDK378 For Cancer supplier
Pharmaceutical Raw Materials Anticancer Drug Raw Ceritinib LDK378 For Cancer supplier Pharmaceutical Raw Materials Anticancer Drug Raw Ceritinib LDK378 For Cancer supplier

Large Image :  Pharmaceutical Raw Materials Anticancer Drug Raw Ceritinib LDK378 For Cancer

Product Details:

Place of Origin: HUBEI,CHINA
Brand Name: HKYC
Certification: ISO 9000, SGS
Model Number: CAS:521-11-9

Payment & Shipping Terms:

Minimum Order Quantity: 10grams
Price: negotiable(best offer will be provided)
Packaging Details: designed disguised packing ways, 100% pass custom guarantee)
Delivery Time: within 24hours after payment confirm
Payment Terms: MoneyGram, Western Union, T/T, Bitcoin
Supply Ability: 1000Kg per Month
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Detailed Product Description
Ceritinib (LDK378): (CAS# 1032900-25-6) Purity:: 99%
MOQ: 100mi Molecular Formula: Ceritinib C28H36ClN5O3S
Source: Ceritinib From China Alias: LDK378
Standard: USP28/BP2003 Appearance: White Crystalline Powder

Pharmaceutical Raw Materials Anticancer Drug Raw Ceritinib LDK378 For Cancer

 

99.9% Purity 1802250-63-0 Ldk378 Ceritinib Intermediate Raw Powder

Anticancer Drug Raw Ceritinib (LDK378) (CAS# 1032900-25-6)

 

Ceritinib (LDK378) (CAS# 1032900-25-6)

Ceritinib Intermediate (CAS# 1802250-63-0)

Ceritinib Product Name LDK378

Ceritinib Molecular Formula C28H36ClN5O3S

Ceritinib Molecular Weight 475.35

Ceritinib Purity: 99%+

Ceritinib Product Specifications: Pharmaceutical Grade

Ceritinib MOQ(Minimum Order Quantity): 100g

Ceritinib Payment: L/C, T/T, Western Union

Ceritinib Shipment: EMS, DHL, FedEx, TNT

Brand: Newbio Pharm-Tech

 

 

Description

Ceritinib (LDK378) is designed to reduce the possibility of forming reactive metabolites and shows undetectable levels of glutathione (GSH) adducts (<1%) in liver microsomes. LDK378 has relatively good metabolic stability, with moderate CYP3A4 (Midazolam substrate) inhibition and hERG inhibition. LDK378 exhibits low plasma clearance in animals (mouse, rat, dog and monkey) compared to liver blood flow, with the oral bioavailability of above 55% in mouse, rat, dog and monkey. LDK378 induces a dose-dependent growth inhibition and tumor regression in the Karpas299 and H2228 rat xenograft models, with no body-weight loss. LDK378 shows no impact on insulin levels or plasma glucose utilization in the mouse upon chronic dosing up to 100 mg/kg.

 

Pharmaceutical Raw Materials Anticancer Drug Raw Ceritinib LDK378 For Cancer

 

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