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Glucocorticoid Steroids Clobetasol Propionate CAS 25122-46-7 for Topical Corticosteroid
Synonyms: 17-propionate;cgp9555;clobesol;pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-me;CLOBESTASOL PROPIONATE;CLOBETASOL-17-PROPIONATE;CLOBETASOLE PROPIONATE;CLOBETASOL PROPIONATE
Chemical Properties White Crystalline Powder
Usage Topical corticosteroid. Glucocorticoid; anti-inflammatory
Clobetasol Propionate Description :
Clobetasol Propionate is a kind of white to light yellow crystalline powder. It is a potent topical corticosteroids. Topical easily absorbed from the skin, so the short-term treatment of intractable skin disease is particularly effective. It has a strong capillary contraction, its anti-inflammatory effects of hydrocortisone 112.5 times. Shuinazhuliu no effect, there is a certain sodium, potassium excretion enhancers. Topical application of beclomethasone loose Shihai DNA synthesis of epidermal cells and inhibit mitosis, which is beclomethasone loose on the proliferation of cell renewal to skin diseases such as psoriasis, characterized by yet another mechanism to produce a therapeutic effect. And has anti-itching and vasoconstriction, reducing overflow and inflammation.
What Is Clobetasol Propionate is Used For?
a) Clobetasol propionate is used to reduce the inflammation, redness,swelling, itching and tenderness associated with skin conditions and is applied locally on the skin.
b) It is a topical corticosteroid, sometimes known as steroids.
c) It is used to treat skin and scalp conditions that have not been effectively treated with other steroids.
d) In general this drug is used to treat eczema, psoriasis, dermatitis and neurodermatitis (skin problems caused by stress or other psychologicalfactors).
What is Anti Inflammatory?
Anti-inflammatory or antiinflammatory refers to the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system.
Non-steroidal anti-inflammatory drugs
Non-steroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase (COX) enzyme. On its own, COX enzyme synthesizes prostaglandins, creating inflammation. In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the pain.
Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. The newer specific COX-inhibitors are not classified together with the traditional NSAIDs even though they presumably share the same mode of action.
On the other hand, there are analgesics that are commonly associated with anti-inflammatory drugs but that have no anti-inflammatory effects. An example is paracetamol (known as acetaminophen in the U.S). As opposed to NSAIDs, which reduce pain and inflammation by inhibiting COX enzymes, paracetamol has - as early as 2006 - been shown to block the reuptake of endocannabinoids, which only reduces pain, likely explaining why it has minimal effect on inflammation.
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